Author

Jiaxi Yao

First Hospital of China Medical UniversityORCID 0000-0002-8023-4338Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:mechanistic / dynamical model· 1 Organism:mouse· 1

Frequent Co-Authors

Chenghan Wang· 1 shared Chenyuan Wang· 1 shared Haixia ZhaoiD· 1 shared Haonan Zhou· 1 shared Huajun Xu· 1 shared Jingman NiiD· 1 shared Jun Jin· 1 shared Kai Xiong· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperImmunology

Chenghan Wang

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2 papers

Recent·Most cited

A feed-forward loop between niche adenosine and Gzmk⁺ CD8 T cells propagates systemic inflammaging

Lin Guo, Rui Zheng, Qianqian Zhan, Xin Yu, Qi Zhang, Jiaxi Yao, Xiaoqing Tan, Xin Li, Ou Zhang, Peiyun Liu, Chenghan Wang, Ye Yao, Rui Ma, Xiao Wu, Chenyuan Wang, , Wenqiang Cao

This study identifies an adenosine-Gzmk axis that drives T cell aging and systemic inflammaging, showing that targeting it can reverse aging phenotypes and extend lifespan in mice.

bioRxiv · Mar 20, 2026 · PreprintImmunology

Application and mechanism of anticancer peptides in organoid models of intrahepatic cholangiocarcinoma

Xuekai Hu, Yue Zhang, Yanchen Li, Qiuxia Zheng, Haixia Zhao, Yun Zhang, Jingman Ni, Jiaxi Yao

This study evaluates the efficacy of anticancer peptides in patient-derived organoids of intrahepatic cholangiocarcinoma, showing their potent anti-tumour effects through direct membrane disruption and apoptosis induction.

Scientific Reports · Jul 1, 2025Peer-reviewedCancer Biology