Yue Zhang

Microbial Invasion and Immunosuppression Drives Adenoma Progression in Early Colorectal Cancer Development

The paper shows bacterial invasion and neutrophil immunosuppression drive adenoma progression in a porcine FAP model using single-cell RNA sequencing and spatial transcriptomics.

Monothiol glutaredoxin DaGrxB couples iron homeostasis with redox balance to orchestrate development and virulence in the peach shoot blight fungus Diaporthe amygdali

Microbial community response and recovery through an aeration-cessation time series in a eutrophic estuary

The paper investigates microbial community response to aeration and its cessation in a eutrophic estuary, showing shifts in community structure and dominance of algae during aeration shutdown.

Ten-Fold Expansion MALDI Mass Spectrometry Imaging of Tissues and Cells at 500 nm Resolution

This paper introduces a novel MALDI-MSI method achieving 500 nm resolution for subcellular imaging in mouse brain tissues and cultured cells.

MARINER: a surround visual stimulator for vision research in aquatic animals

MARINER is a visual stimulator for aquatic animals that improves underwater visual stimulation and reveals new insights into larval zebrafish visual field and colorblindness during optokinetic responses.

A Sandwich-Structured Silk Fibroin Mesh with ROS-Responsive and Immunoregulatory Functions for Pelvic Floor Repair

This paper develops a ROS-responsive silk fibroin mesh with immunoregulatory properties for pelvic floor repair, showing improved immune modulation and tissue integration.

Blocking SHP2 benefits FGFR2 inhibitor and overcomes its resistance in FGFR2-amplified gastric cancer

This paper shows that blocking SHP2 enhances FGFR2 inhibitor effectiveness and overcomes resistance in FGFR2-amplified gastric cancer by inhibiting feedback pathways and boosting T cell immunity.

An activated wheat CCG10-NLR immune receptor forms an octameric resistosome

Activated wheat CCG10-NLR immune receptor WAI3 and Arabidopsis RPS2 assemble into octameric calcium-permeable resistosomes with an inverted coiled-coil domain topology associated with lacking the conserved EDVID motif.

AAV-Mediated Dual-Gene Therapy Restores Metabolic Function in Mice with Propionic Acidemi

This study demonstrates that dual-gene AAV therapy restores metabolic function and shows long-term safety in a mouse model of propionic acidemia.

Accessible and reproducible mesoscale fMRI at 5.0 T: A Pulseq-based open framework for human laminar mapping

This paper develops an open-source framework for mesoscale fMRI at 5.0 T, demonstrating reliable laminar activation patterns comparable to 7.0 T systems.

Application and mechanism of anticancer peptides in organoid models of intrahepatic cholangiocarcinoma

This study evaluates the efficacy of anticancer peptides in patient-derived organoids of intrahepatic cholangiocarcinoma, showing their potent anti-tumour effects through direct membrane disruption and apoptosis induction.

Neuronal TORC1 modulates longevity via AMPK and cell nonautonomous regulation of mitochondrial dynamics in C. elegans

PLOS ONETitle - Optimization of the flash extraction of flavonoids from the leaves of Salix babylonica using the response surface method and an evaluation of the leaves high antioxidant activity

This study optimizes flash extraction of flavonoids from Salix babylonica leaves using response surface methodology and evaluates their antioxidant activity.

A spatio-temporal model for spontaneous thrombus formation in cerebral aneurysms

The paper develops a spatio-temporal model to simulate thrombus formation in cerebral aneurysms using CFD and biomechanical processes, accurately reproducing patient-specific thrombus shapes and volumes.