Cell BiologyJournal of Biological ChemistryPeer-reviewed
Activation of pro-survival autophagy by a small molecule promoting p62 oligomerisation
Johan Panek, Edward Fielder, Congsing Sun…·Viktor I. Korolchuk
The paper identifies SQ-1 as a small molecule that activates autophagy by promoting p62 oligomerisation, improving mitochondrial clearance and cell viability in NPC1 disease models.
DOI 10.1016/j.jbc.2026.113430