Author

Gavin John Miller

Keele UniversityORCID 0000-0001-6533-3306Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Turner· 1 shared Antonella BisioiD· 1 shared Congsing Sun· 1 shared Courtney J. Mycroft‐WestiD· 1 shared Cristina GardiniiD· 1 shared Edward FielderiD· 1 shared Edwin Alexander YatesiD· 1 shared Elena UrsoiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBiochemistry

A. Turner

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2 papers

Recent·Most cited

Activation of pro-survival autophagy by a small molecule promoting p62 oligomerisation

Johan Panek, Edward Fielder, Congsing Sun, Steph Crabtree, Tetsushi Kataura, Niall Wilson, Lakshana Baheerathan, Jiangyu Tang, Laura K. Booth, Wyatt W. Yue, Gavin David Richardson, Lauren Holder, Gavin John Miller, Jóhannes Reynisson, Sovan Sarkar, Viktor I. Korolchuk

The paper identifies SQ-1 as a small molecule that activates autophagy by promoting p62 oligomerisation, improving mitochondrial clearance and cell viability in NPC1 disease models.

Journal of Biological Chemistry · Aug 11, 2026Peer-reviewedCell Biology

Enzymatic access to the rare ΔUA (1->4) Glc 3, 6, N-sulfated heparin disaccharide, implications for heparin quality control

Taran Kaur Kandola, Courtney J. Mycroft‐West, Marcelo Andrade de Lima, A. Turner, Cristina Gardini, Elena Urso, Gavin John Miller, Antonella Bisio, Edwin Alexander Yates, Marco Guerrini, L. Wu, Mark Andrew Skidmore

This study characterizes a Bacteroides eggerthii lyase that efficiently cleaves heparin to release a rare anticoagulant disaccharide, offering improved methods for quality control.

bioRxiv · Sep 26, 2024 · PreprintBiochemistry