The PHD3-FOXO3 axis modulates the interferon type I response in microglia aggravating Alzheimer's disease progression
Manuel A. Sánchez-García, Nieves Lara-Ureña, Rosana March‐Díaz, Clara Ortega‐de San Luis, Silvia Quiñones-Cañete, Juan M. Barba-Reyes, Daniel Cabello-Rivera, Ana María Muñoz-Cabello, Bella Mora-Romero, Carmen Romero‐Molina, Antonio Heras‐Garvin, Victoria Navarro, José López‐Barneo, Marisa Vizuete, Javier Vitórica, , Alberto Pascual
This study identifies the PHD3-FOXO3 axis as a regulator of the interferon type I response in microglia, which contributes to Alzheimer's disease progression.
bioRxiv · Oct 1, 2024 · PreprintNeuroscience