Cell BiologyNature Cell BiologyPeer-reviewed
Lysosome damage triggers acute formation of ER to lysosomes membrane tethers mediated by the bridge-like lipid transport protein VPS13C
Xinbo Wang, Peng Xu, Amanda Bentley‐DeSousa…·Pietro V. De Camilli
The paper shows that VPS13C senses lysosome damage, relocates to lysosomes, and tethers them to the ER, suggesting a protective lipid transport response.
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