Nathan M. Stewart

This study shows that a mutation in FicD causes diabetes by disrupting BiP AMPylation and pancreatic endocrine homeostasis in mice.

This study investigates the role of FicD in regulating BiP AMPylation and UPR signaling in mouse embryonic fibroblasts under different stress conditions, revealing its impact on stress recovery and protein secretion.

This study shows FicD regulates UPR responses in the murine liver during mild stress but not chronic or acute UPR induction.

Candidate Explorer identifies causative mutations for immune phenotypes by integrating multiple data features into a score, improving mutation-phenotype association verification in mice.