Author

Ralph A.W. Rupp

Ludwig-Maximilians-Universität MünchenORCID 0000-0002-8068-9957Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 2 Bioinformatics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Assay:ATAC-seq· 1 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Assay:ChIP-seq· 1 Approach:experimental assay· 1

Frequent Co-Authors

Axel ImhofiD· 2 shared Daniil PokrovskyiD· 2 shared Janet TaitiD· 2 shared Tobias StraubiD· 2 shared Alessandro AngerilliiD· 1 shared Barbara Hoelscher· 1 shared Carmen Marthen· 1 shared Carolin LoosiD· 1 shared

Activity by Year

2020-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersMolecular Biology

Axel ImhofORCID

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4 papers

Recent·Most cited

Catalytic activity of KMT5B promotes cilia tuft formation without affecting chromatin accessibility of ciliary genes

Janet Tait, Carmen Marthen, Barbara Hoelscher, Tobias Straub, Ralph A.W. Rupp

The paper shows that KMT5B promotes cilia tuft formation independently of chromatin accessibility changes at ciliary genes.

bioRxiv · Mar 18, 2025 · PreprintDevelopmental Biology

Mitotic activity shapes stage-specific histone modification profiles during Xenopus embryogenesis

Daniil Pokrovsky, Ignasi Forné, Tobias Straub, Axel Imhof, Ralph A.W. Rupp

The paper shows that inhibiting cell proliferation during Xenopus embryogenesis leads to abnormal histone modification profiles, suggesting that cell division influences chromatin maturation and developmental decisions.

PLoS Biology · Sep 7, 2021Peer-reviewedMolecular Biology

Histone H4K20 methylation synchronizes cytoskeletal dynamics with cell cycle phases during epidermal differentiation

Alessandro Angerilli, Janet Tait, Julian Berges, Irina Shcherbakova, Tamás Schauer, Pawel Smialowski, Ohnmar Hsam, Edith Mentele, Dario Nicetto, Ralph A.W. Rupp

bioRxiv · Dec 1, 2020 · PreprintDevelopmental Biology

Computational modeling reveals cell-cycle dependent kinetics of H4K20 methylation states during Xenopus embryogenesis

Lea Schuh, Carolin Loos, Daniil Pokrovsky, Axel Imhof, Ralph A.W. Rupp, Carsten Marr

The paper models H4K20 methylation kinetics during Xenopus embryogenesis, showing demethylation is essential in non-cycling cells but dispensable in rapidly dividing cells.

Cell Systems · Dec 1, 2020Peer-reviewedBioinformatics