Tobias Straub

The paper identifies PCDH10 as a regulator of neuronal clustering during cortical neuron migration, showing its interaction with FLRT proteins and its role in cortical folding.

This study identifies Aquarius RNA helicase as essential for maintaining genomic resilience and pluripotent stem cell identity by resolving transcription-replication conflicts.

The paper shows that periweaning diet activates an IFNγ-mediated circuit in cDC1 that promotes effector memory CD8 T cell homeostasis through immunogenic maturation.

The paper identifies DDK-mediated phosphorylation of INO80's Arp8 subunit, which stabilizes the complex and regulates nucleosome spacing at replication origins, enhancing replication efficiency and stress response.

The paper shows that combining progenitor expansion with adhesion-controlled neuronal migration enhances cortex folding in mice, leading to sulci and gyri formation.

The paper identifies IFN-induced activation of dendritic cells and monocytes after yellow fever vaccination as correlated with early protective antibody responses.

The paper shows that centrosomes in non-dividing cells can fracture under mechanical stress during cell navigation, and Dyrk3 prevents this fracturing to maintain cellular function.

The paper shows that KMT5B promotes cilia tuft formation independently of chromatin accessibility changes at ciliary genes.

This study identifies KRT17 as a mediator of platinum resistance and a biomarker for targeted therapy in ovarian cancer using organoid models and clinical data.

This study identifies H3K27ac as an epigenetic barrier to reprogramming-induced cell fate changes using an AI-based approach and shows that reducing H3K27ac improves reprogramming efficiency.

This study shows that H3K4 methylation acts as an epigenetic memory to support zygotic genome activation and embryonic development in Xenopus laevis.

This paper enhances biomedical question-answering using a keyword frequency-driven prompt strategy to improve LLM responses and reduce hallucinations.

This study investigates neuronal hyperactivity in human cerebral organoids derived from individuals with grey matter heterotopia, identifying functional and structural changes linked to the condition.

The paper identifies genetically and spatially distinct BLA neuron subpopulations and their roles in food consumption and social behavior.

This study shows that Bru1 regulates cytoskeleton dynamics and a splicing transition during Drosophila flight muscle development, leading to structural defects when disrupted.

This study investigates the biogenesis and function of nucleosome arrays in yeast, showing that transcription and chromatin remodeling complexes like INO80 shape nucleosome positioning and protect the genome.

The paper shows that inhibiting cell proliferation during Xenopus embryogenesis leads to abnormal histone modification profiles, suggesting that cell division influences chromatin maturation and developmental decisions.

The paper identifies cell type-specific complement expression patterns in healthy and diseased retinas across human and murine models, highlighting age-related and disease-induced changes.

The paper identifies genome-wide phased nucleosome arrays in Drosophila, revealing a novel sequence motif and the role of the zinc finger protein Phaser in their formation.

This study shows that ACF1-containing chromatin remodeling complexes repress gene expression by maintaining a repressive chromatin state in Drosophila.

This study examines nucleolus-associated chromosomal domains in human cells during senescence, finding that their association is largely maintained despite nuclear reorganization.