Author

Hillary Hoyt

ORCID 0000-0002-8084-7249Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1

Frequent Co-Authors

Amanda L. Halfond· 1 shared Hannah MageriD· 1 shared Huan Qiu· 1 shared Huanying Gary Ge· 1 shared John R. LydeardiD· 1 shared Julia Etchin· 1 shared Julian Scherer· 1 shared Juliana M. Xavier-FerrucioiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Amanda L. Halfond

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1 paper

Recent·Most cited

Integrating Human Genetics and Protective Genome Editing to Enable ADGRE2-Directed AML Therapy

Yonina Keschner, Julia Etchin, Mariana Camoesas Silva, Hannah Mager, Hillary Hoyt, Juliana M. Xavier-Ferrucio, Nathan A. Manalo, Amanda L. Halfond, Huan Qiu, Ruijia Wang, Michelle I. Lin, Huanying Gary Ge, Julian Scherer, Tirtha Chakraborty, John R. Lydeard

This study evaluates ADGRE2 as an AML target, showing efficient gene editing in HSPCs to protect against myelotoxicity and developing ADGRE2-specific CAR T cells for therapy.

bioRxiv · Aug 21, 2025 · PreprintCancer Biology