Author

Julia Etchin

Boston Children's Hospital

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 1 Cancer Biology· 1 Genetics· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Assay:ATAC-seq· 1 Assay:bulk RNA-seq· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

Huanying Gary Ge· 2 shared John R. LydeardiD· 2 shared Tirtha ChakrabortyiD· 2 shared Yonina KeschneriD· 2 shared Abhinav DhalliD· 1 shared Alexander J. Murison· 1 shared Alfred Thomas LookiD· 1 shared Alyssa Pyclik· 1 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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2 shared papersGenetics

Huanying Gary Ge

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

A Human Genetics Framework for De-risking Gene Editing Targets for Hematopoietic Cell and Gene Therapy

Abhinav Dhall, Alyssa Pyclik, Matthew H. Ung, Julia Etchin, Yonina Keschner, Huanying Gary Ge, Tirtha Chakraborty, John R. Lydeard

The paper develops a proteogenomic framework to identify dispensable genes for safer gene editing in hematopoietic therapies, identifying 237 candidates including LY75.

bioRxiv · Dec 17, 2025 · PreprintGenetics

Integrating Human Genetics and Protective Genome Editing to Enable ADGRE2-Directed AML Therapy

Yonina Keschner, Julia Etchin, Mariana Camoesas Silva, Hannah Mager, Hillary Hoyt, Juliana M. Xavier-Ferrucio, Nathan A. Manalo, Amanda L. Halfond, Huan Qiu, Ruijia Wang, Michelle I. Lin, Huanying Gary Ge, Julian Scherer, Tirtha Chakraborty, John R. Lydeard

This study evaluates ADGRE2 as an AML target, showing efficient gene editing in HSPCs to protect against myelotoxicity and developing ADGRE2-specific CAR T cells for therapy.

bioRxiv · Aug 21, 2025 · PreprintCancer Biology

Distinct gene regulatory networks govern hematopoietic and leukemia stem cells

Boyang Zhang, Alexander J. Murison, Angelica Varesi, Naoya Takayama, Liqing Jin, Nathan Mbong, Erwin M. Schoof, Stephanie Zhi-Juan Xie, Amanda Mitchell, Julia Etchin, Alfred Thomas Look, Mathieu Lupien, Mark David Minden, Jean C. Y. Wang, Peter W. Zandstra, , Stanley W.K. Ng

This study identifies distinct gene regulatory networks in hematopoietic stem cells and leukemia stem cells using integrated gene expression and chromatin accessibility data from AML patients and human umbilical cord blood.

bioRxiv · Sep 28, 2024 · PreprintBioinformatics