Hanbo Chen

NeuroXiv provides an AI-powered database of neuron morphologies from mouse brains, enabling dynamic analysis and comparison across a standardized atlas.

The paper defines neuron connectivity types (c-types) using morphology and connectivity data, showing they better capture subtype distinctions than other features.

BigNeuron benchmarks automatic neuron reconstruction algorithms using gold standard annotations and image quality metrics, showing that consensus methods outperform individual algorithms.

The paper maps excitatory and inhibitory synapses across dendritic trees of cortical neurons and finds local balance in their ratio despite domain-specific density variations.

NeuronStitcher is a software suite that stitches non-overlapping neuron fragments from 3D image sections to reconstruct large and complex neurons efficiently.