Brain InformaticsNeurosciencePeer-reviewed journal article
Fast Assembling of Neuron Fragments in Serial 3D Sections
Hanbo CheniD, Daniel Maxim IasconeiD, Nuno Maçarico da CostaiD, Ed S. LeiniD, Tianming LiuiD, Hanchuan PengiD
Abstract
AbstractReconstructing neurons from 3D image-stacks of serial sections of thick brain tissue is very time-consuming and often becomes a bottleneck in high-throughput brain mapping projects. We developed NeuronStitcher, a software suite for stitching non-overlapping neuron fragments reconstructed in serial 3D image sections. With its efficient algorithm and user-friendly interface, NeuronStitcher has been used successfully to reconstruct very large and complex human and mouse neurons.
- organism: human
- organism: mouse
- assay: imaging
- research focus: deconvolution
- approach: experimental assay
- Citations
- 11
- FWCI
- 0.64
- Field percentile
- top 31%
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