Validation of Serum Neurofilament Light Chain as a Biomarker of Parkinson's Disease Progression
Brit Mollenhauer, Mohammed Dakna, Niels Kruse, Douglas R Galasko, Tatiana Foroud, Henrik Zetterberg, Sebastian Schade, Roland G. Gera, Wenting Wang, Feng Gao, Mark A. Frasier, Lana M. Chahine, Christopher S. Coffey, Andrew Singleton, Tanya Simuni, , Danielle L. Graham
This paper validates serum neurofilament light chain (NfL) as a biomarker for Parkinson's disease progression, showing increased levels in PD patients compared to healthy controls and a longitudinal increase correlating with clinical severity.
Movement Disorders · Aug 15, 2020Peer-reviewedNeuroscience