Author

Sebastian Schade

Paracelsus Elena Klinik KasselORCID 0000-0002-6316-6804Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Research Focus:differential expression· 1 Assay:metabolomics· 1 Assay:metagenomics· 1

Frequent Co-Authors

Brit MollenhaueriD· 2 shared Claudia TrenkwalderiD· 2 shared Andrew D. SiderowfiD· 1 shared Andrew SingletoniD· 1 shared Anna Heintz‐BuschartiD· 1 shared Annegrät Daujeumont· 1 shared Annette JanzeniD· 1 shared Arthur W. TogaiD· 1 shared

Activity by Year

2020-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersSystems Biology

Brit MollenhauerORCID

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2 papers

Recent·Most cited

Integrated multi-omics highlights alterations of gut microbiome functions in prodromal and idiopathic Parkinson's disease

Rémy Villette, Júlia Ortís Sunyer, Polina V. Novikova, Velma T. E. Aho, В. А. Петров, Oskar Hickl, Susheel Bhanu Busi, Charlotte De Rudder, Benoit Josef Kunath, Anna Heintz‐Buschart, Jean‐Pierre Trezzi, Rashi Halder, Christian Jäger, Laura Lebrun, Annegrät Daujeumont, , Paul Wilmes

The paper uses integrated multi-omics to identify functional gut microbiome alterations in Parkinson's disease and prodromal stages, finding changes in metabolites and microbial gene transcripts.

Microbiome · Oct 6, 2025Peer-reviewedSystems Biology

Validation of Serum Neurofilament Light Chain as a Biomarker of Parkinson's Disease Progression

Brit Mollenhauer, Mohammed Dakna, Niels Kruse, Douglas R Galasko, Tatiana Foroud, Henrik Zetterberg, Sebastian Schade, Roland G. Gera, Wenting Wang, Feng Gao, Mark A. Frasier, Lana M. Chahine, Christopher S. Coffey, Andrew Singleton, Tanya Simuni, , Danielle L. Graham

This paper validates serum neurofilament light chain (NfL) as a biomarker for Parkinson's disease progression, showing increased levels in PD patients compared to healthy controls and a longitudinal increase correlating with clinical severity.

Movement Disorders · Aug 15, 2020Peer-reviewedNeuroscience