Genetic characterization of outbred Sprague Dawley rats and utility for genome-wide association studies
Alexander F. Gileta, Christopher J. Fitzpatrick, Apurva S. Chitre, Celine L. St. Pierre, Elizabeth V. Joyce, Rachael J. Maguire, Africa M. McLeod, Natalia M. Gonzales, April E. Williams, Jonathan D. Morrow, Terry E. Robinson, Shelly B. Flagel, Abraham A. Palmer
The paper genotypes over 4,000 Sprague Dawley rats to characterize genetic diversity and performs GWAS on Pavlovian conditioned approach behavior, identifying 46 significant loci.
PLoS Genetics · May 31, 2022Peer-reviewedGenetics