Discovery and engineering of small SlugCas9 with broad targeting range and high specificity and activity
Ziying Hu, Chengdong Zhang, Shuai Wang, Siqi Gao, Jingjing Wei, Miaomiao Li, Linghui Hou, Huilin Mao, Yanyan Wei, Tao Qi, Hongmao Liu, Dong Liu, Feng Lan, Daru Lu, Hongyan Wang, , Yongming Wang
The paper identifies and engineers a compact SlugCas9 variant with broad targeting range, high specificity, and activity for genome editing.
Nucleic Acids Research · Feb 23, 2021Peer-reviewedGenetics