Author

Chandrashekhar Pasare

Cincinnati Children's Hospital Medical CenterORCID 0000-0002-8142-2488Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Research Focus:host-pathogen & immune response· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Aakanksha Jain· 1 shared Alexander V. Chervonsky· 1 shared Amanpreet S. Chawla· 1 shared Andrew J. CarrolliD· 1 shared Andrew Oberst· 1 shared Ann‐Kathrin EisfeldiD· 1 shared Bayard L. Powell· 1 shared Benjamin WronowskiiD· 1 shared

Activity by Year

2018-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperImmunology

Aakanksha Jain

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2 papers

Recent·Most cited

Cancer BiologyJCI InsightPeer-reviewedFeb 23, 2026

PTPN11 Mutation Clonal Hierarchy in Acute Myeloid Leukemia

Sydney Fobare, Chia Sharpe, K. R. Quinn…·John C. Byrd

This study identifies PTPN11 mutations as potential initiating events in AML when paired with NPM1 mutations, revealing their co-driver role and immune diversity in patient samples.

3 citations

mousewhole-genome sequencing

ImmunologybioRxivPreprintNov 26, 2018

T cells instruct dendritic cells to produce inflammasome independent IL-1β causing systemic inflammation

Aakanksha Jain, Ricardo A. Irizarry-Caro, Amanpreet S. Chawla…·Chandrashekhar Pasare

This study identifies a T cell-instructed, inflammasome-independent pathway of IL-1β production in dendritic cells that drives systemic inflammation in autoimmune diseases.

DOI 10.1101/475517

mouseexperimental assay