Author

Sean Lando Levin Seegert

Universitätsmedizin GreifswaldORCID 0000-0002-8143-6038Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Assay:proteomics· 1

Frequent Co-Authors

Barbara M. BrökeriD· 2 shared Liliane Maria Fernandes de OliveiraiD· 2 shared Murthy N. DarisipudiiD· 2 shared Shruthi PeringatharaiD· 2 shared Silva HoltfreteriD· 2 shared Stefan GroßiD· 2 shared Stefan WeißiD· 2 shared Antje VogelgesangiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 43 mutual co-author links

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2 shared papersImmunology

Barbara M. BrökerORCID

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2 papers

Recent·Most cited

A mouse-adapted Staphylococcus aureus strain enables lifelong neonatal colonization and elicits a Th17-dominated immune response

Liliane Maria Fernandes de Oliveira, Sean Lando Levin Seegert, Murthy N. Darisipudi, Shruthi Peringathara, Frieder Schmiedeke, Daniel M. Mrochen, Stefan Groß, Stefan Weiß, Barbara M. Bröker, Silva Holtfreter

This study establishes a neonatal S. aureus colonization model in mice using a mouse-adapted strain, showing persistent colonization and a Th17-dominated immune response.

bioRxiv · Sep 2, 2026 · PreprintImmunology

Spontaneous preputial gland infection in Staphylococcus aureus-colonized male C57BL/6 mice triggers a Th17-driven immune response

Liliane Maria Fernandes de Oliveira, Shruthi Peringathara, Murthy N. Darisipudi, Sean Lando Levin Seegert, Elisa Bludau, Stefan Weiß, Antje Vogelgesang, Janosch Schoon, Stefan Groß, Björn Corleis, Barbara M. Bröker, Silva Holtfreter

This study shows that S. aureus colonization in male mice leads to spontaneous preputial gland infections driven by a Th17 immune response that fails to clear the bacteria.

bioRxiv · Sep 5, 2025 · PreprintMicrobiology