Barbara M. Bröker

This study establishes a neonatal S. aureus colonization model in mice using a mouse-adapted strain, showing persistent colonization and a Th17-dominated immune response.

This study shows that S. aureus SplB induces asthma-like symptoms in mice, requiring proteolytic activity and adaptive immunity, suggesting a direct role of bacterial allergens in asthma.

This study identifies immunoglobulin sub-class levels as key factors in inter-donor plasma variability using longitudinal proteomic data from two labs.

This study shows that SKP2 limits autophagy during S. aureus infection by stabilizing and translocating to the cytoplasm, reducing LC3-II levels and intracellular bacterial survival.

This study shows that S. aureus colonization in male mice leads to spontaneous preputial gland infections driven by a Th17 immune response that fails to clear the bacteria.

This study examines the effects of obesity on hippocampal-dependent learning and neurogenesis in ob/ob mice, finding reduced neurogenesis but no impairment in spatial learning.