Murthy N. Darisipudi

This study establishes a neonatal S. aureus colonization model in mice using a mouse-adapted strain, showing persistent colonization and a Th17-dominated immune response.

This study shows that S. aureus SplB induces asthma-like symptoms in mice, requiring proteolytic activity and adaptive immunity, suggesting a direct role of bacterial allergens in asthma.

This study shows that S. aureus colonization in male mice leads to spontaneous preputial gland infections driven by a Th17 immune response that fails to clear the bacteria.