Author

Petr Kaláb

Johns Hopkins UniversityORCID 0000-0002-8145-7728Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Organism:Drosophila· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1

Frequent Co-Authors

Lindsey R. HayesiD· 2 shared Anne C Starner· 1 shared Benjamin L. ZaepfeliD· 1 shared Christopher J. DonnellyiD· 1 shared Daniela C. ZarnescuiD· 1 shared Danielle de Paula MoreiraiD· 1 shared Dominic L. JulianiD· 1 shared Eric B. AlsopiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersNeuroscience

Lindsey R. HayesORCID

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2 papers

Recent·Most cited

NeurosciencebioRxivPreprintJun 25, 2026

ADAR2-Mediated RNA Editing Promotes TDP-43 Nuclear Export and Alters RNA Binding

Stephen R. Moore, Dominic L. Julian, Eric B. Alsop…·Rita Sattler

This study shows ADAR2-mediated RNA editing promotes TDP-43 nuclear export and alters its RNA binding, contributing to neurodegenerative disease mechanisms.

DOI 10.64898/2026.06.22.730622

humanDrosophila

Cell BiologybioRxivPreprintApr 2, 2025

5-ethynyluridine perturbs nuclear RNA metabolism to promote the nuclear accumulation of TDP-43 and other RNA binding proteins

Lindsey R. Hayes, Benjamin L. Zaepfel, Lauren Duan…·Petr Kaláb

This study shows that 5-ethynyluridine (5EU) causes nuclear accumulation of TDP-43 and other RNA-binding proteins by altering RNA metabolism and splicing.

DOI 10.1101/2025.04.02.646885

humanbulk RNA-seq