Author

Andrea J. Manrique-Rincón

University of CambridgeORCID 0000-0002-8146-1495Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Assay:fluorescence / live-cell microscopy· 1

Frequent Co-Authors

Anneliese O. SpeakiD· 2 shared Anke HusmanniD· 1 shared Ben Foster· 1 shared Carla P. JonesiD· 1 shared Craig A. GlastonburyiD· 1 shared David A. GouldingiD· 1 shared David J. AdamsiD· 1 shared F. CisterninoiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersImmunology

Anneliese O. SpeakORCID

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2 papers

Recent·Most cited

ImmunologybioRxivPreprintFeb 11, 2026

Multiplexed high-content imaging uncovers morphological diversity of lymphocyte activation and dysfunction

Julie C. Matte, Olivier B. Bakker, Madeline Ohl…·Gosia Trynka

The paper introduces TGlow, a high-content imaging platform for single-cell phenotyping of human lymphocytes, revealing distinct morphological states and drug responses.

DOI 10.64898/2026.02.10.704860

humanimaging

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ImmunologyiSciencePeer-reviewedJun 12, 2025

Simulating CD8 T Cell Exhaustion: A Comprehensive Approach

Andrea J. Manrique-Rincón, Ben Foster, Stuart D. Horswell…·Anneliese O. Speak

The paper develops an in vitro model of CD8 T cell exhaustion and identifies a gene signature that defines the exhausted state in both in vitro and in vivo settings, with validation in human tumor samples.

4 citations

humanbulk RNA-seq

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