Haote Li

This paper uses a machine learning model to generate new anti-PD-1 antibodies with improved potency, validated through molecular dynamics simulations and experimental testing.

This paper determines the crystal structure of rademikibart Fab-IL-4Rα complex and performs MD simulations to show its superior binding and inhibition of IL-4R compared to dupilumab.

QOBRA is a quantum autoencoder for de novo molecular design that generates valid, novel molecules from limited datasets, demonstrating the potential of quantum computing in molecular synthesis.