Author

Pulan Liu

Yale UniversityORCID 0000-0003-0046-6997Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:deep learning· 2 Organism:human· 2 Research Focus:protein structure prediction· 2 Research Focus:cell type annotation· 1 Assay:cryo-EM· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

Shaogeng TangiD· 2 shared Anna J. WoodiD· 1 shared Christopher Bunick· 1 shared Haote LiiD· 1 shared Jimin WangiD· 1 shared Rithik E. CastelinoiD· 1 shared Taylor R. GierkeiD· 1 shared Víctor S. BatistaiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersBiochemistry

Shaogeng TangORCID

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2 papers

Recent·Most cited

BiochemistrybioRxivPreprintAug 4, 2026

Humanized Anti-PD-1 Antibodies Generated Using The Conditional Kernel-Elastic Autoencoder

Yuanjun Shi, Haote Li, Pulan Liu…·Víctor S. Batista

This paper uses a machine learning model to generate new anti-PD-1 antibodies with improved potency, validated through molecular dynamics simulations and experimental testing.

DOI 10.64898/2026.08.03.742579

humanproteomics

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BiochemistrybioRxivPreprintMay 15, 2026

Structure and inhibition of the sperm TMEM95-FIMP complex in mammalian fertilization

Pulan Liu, Rithik E. Castelino, Taylor R. Gierke…·Shaogeng Tang

This study identifies FIMP as a binding partner of TMEM95, determines their complex structure, and shows that disrupting this interaction inhibits sperm-egg fusion.

2 citations

humanmouse

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