Andrea Legati

This study uses single-cell RNA sequencing to analyze mtDNA heteroplasmy in fibroblasts, revealing cell-to-cell variability and sample-specific transcriptional responses.

This study shows that axon length in human motor neurons affects their homeostatic mechanisms, revealing length-dependent molecular adaptations in cytoskeleton, translation, and mitochondria.

GARFIELD-NGS uses deep learning to filter false positive variants in exome sequencing data, outperforming existing methods and working at low coverage.