Ciro Chiappini

Immune reprogramming of 3D tumor models via optoporation-mediatedtargeted gene delivery to macrophages

This paper develops a method to deliver genes specifically to macrophages in 3D tumor models, altering the tumor microenvironment to reduce tumorigenicity.

Morphomolecular Longitudinal Endoscopy of Carcinogenesis

This paper introduces a label-free endoscopic platform combining Raman spectroscopy and OCT to track morphomolecular changes in real-time during carcinogenesis, enabling early cancer detection.

NoButter: An R package for reducing transcript dis-persion in CosMx Spatial Molecular Imaging Data

NoButter reduces transcript dispersion in CosMx Spatial Molecular Imaging data by excluding high-dispersion Z-slices, improving data quality.

Axonal length determines distinct homeostatic phenotypes in human iPSC derived motor neurons on a bioengineered platform

This study shows that axon length in human motor neurons affects their homeostatic mechanisms, revealing length-dependent molecular adaptations in cytoskeleton, translation, and mitochondria.