Author

John D. Crispino

St. Jude Children's Research HospitalORCID 0000-0002-8182-8306Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:genetic perturbation / CRISPR· 1 Organism:mouse· 1

Frequent Co-Authors

Te LingiD· 2 shared Amha AtakilitiD· 1 shared Bridget Kelly MarcellinoiD· 1 shared Dean SheppardiD· 1 shared Joshua N. LeonardiD· 1 shared Kelly A. Sarnese· 1 shared Lahiri Konada· 1 shared Lyudmila G. Tsurkan· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersCell Biology

Te LingORCID

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2 papers

Recent·Most cited

Inhibition of the EBF1-ITGB8 Axis in Bone Marrow Niche Ameliorates Hallmarks of Myelofibrosis

Lyudmila G. Tsurkan, Mélodie Douté, Nicholas Morchel, Lahiri Konada, Rashid Mehmood, Te Ling, Amha Atakilit, Bridget Kelly Marcellino, Ronald Hoffman, Peter Vogel, Dean Sheppard, John D. Crispino, Marta Derecka

This study identifies EBF1 and ITGB8 as key regulators of BM fibrosis in myelofibrosis and shows their inhibition reduces disease features in mouse models.

bioRxiv · Feb 17, 2026 · PreprintCell Biology

Building synthetic biosensors using red blood cell proteins

Taylor B. Dolberg, Taylor F. Gunnels, Te Ling, Kelly A. Sarnese, John D. Crispino, Joshua N. Leonard

This study develops RBC-based biosensors using membrane proteins retained through erythropoiesis, demonstrating in vitro and in vivo functionality for non-invasive diagnostics.

ACS Synthetic Biology · Mar 27, 2024Peer-reviewedSynthetic Biology