Synthetic BiologyNature CommunicationsPeer-reviewed
dFLASH; dual FLuorescent transcription factor Activity Sensor for Histone integrated live-cell reporting and high-content screening
Timothy P. Allen, Alison E. Roennfeldt, Moganalaxmi Reckdharajkumar…·David C. Bersten
The paper introduces dFLASH, a tool for live-cell reporting of transcription factor activity, demonstrating its use in sensing HIF and PGR activities and screening for HIF pathway modulators.