Author

Ehsan Irani

Max Delbrück CenterORCID 0000-0002-8194-960XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:Hi-C· 2 Research Focus:benchmarking· 1 Assay:ChIP-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Andrea M. ChiarielloiD· 2 shared Mario NicodemiiD· 2 shared Simona BiancoiD· 2 shared Aleksandra A. KolodziejczykiD· 1 shared Alex AbrahamiD· 1 shared Alexander KukaleviD· 1 shared Altuna AkaliniD· 1 shared Ana PomboiD· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersMolecular Biology

Andrea M. ChiarielloORCID

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2 papers

Recent·Most cited

Loop-extrusion and polymer phase-separation can co-exist at the single-molecule level to shape chromatin folding

Mattia Conte, Ehsan Irani, Andrea M. Chiariello, Alex Abraham, Simona Bianco, Andrea Esposito, Mario Nicodemi

The paper compares loop-extrusion and polymer phase-separation models against chromatin data, finding they can co-exist in shaping single-cell chromatin architecture.

Nature Communications · Jul 13, 2022Peer-reviewedMolecular Biology

Cell-type specialization in the brain is encoded by specific long-range chromatin topologies

Warren Winick‐Ng, Alexander Kukalev, Izabela Harabula, Luna Zea Redondo, Dominik Szabó, Mandy Meijer, Leonid Serebreni, Yingnan Zhang, Simona Bianco, Andrea M. Chiariello, Ibai Irastorza-Azcárate, Luca Fiorillo, Francesco Musella, Christoph J. Thieme, Ehsan Irani, , Ana Pombo

The paper investigates cell-type specific 3D chromatin structures in the brain using immunoGAM, finding TAD melting, neuron-specific contacts, and compartmentalization patterns related to gene expression and neurodegenerative diseases.

bioRxiv · Apr 2, 2020 · PreprintMolecular Biology