Author

Aileen Julia Riesle

University of FreiburgORCID 0000-0002-8195-1291Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 2 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Research Focus:gene regulatory network inference· 3 Approach:statistical model· 3 Assay:ATAC-seq· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:zebrafish· 2 Research Focus:cell type annotation· 1

Frequent Co-Authors

Anna GebhardiD· 2 shared Björn Andreas GrüningiD· 2 shared Daria OnichtchoukiD· 2 shared Helge HassiD· 2 shared Jens TimmeriD· 2 shared Marcus RosenblattiD· 2 shared Marina VeiliD· 2 shared Meijiang GaoiD· 2 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersDevelopmental Biology

Anna GebhardORCID

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3 papers

Recent·Most cited

Molecular BiologybioRxivPreprintDec 23, 2025

The transcription of a single olfactory receptor per neuron is enforced by epigenetic silencing of their enhancers

Francesco Tabaro, Basilia Acurzio, Aileen Julia Riesle…·Mathieu Boulard

This study identifies TRIM66 as a key factor enforcing monogenic expression of olfactory receptors through epigenetic silencing of super-enhancers, impacting axonal projections and behavior.

DOI 10.64898/2025.12.22.695993

mousebulk RNA-seq

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Developmental BiologyNature CommunicationsPeer-reviewedSep 14, 2023

Activator-blocker model of transcriptional regulation by pioneer-like factors

Aileen Julia Riesle, Meijiang Gao, Marcus Rosenblatt…·Daria Onichtchouk

The paper investigates how Pou5f3 and Nanog regulate enhancer types during zygotic genome activation through an activator-blocker mechanism.

16 citations

zebrafishATAC-seq

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Developmental BiologyNature CommunicationsPeer-reviewedFeb 10, 2022

Pou5f3 and Sox19b determine gene expression repertoire at Zygotic Genome Activation

Meijiang Gao, Marina Veil, Marcus Rosenblatt…·Daria Onichtchouk

The paper shows Pou5f3 and Sox19b independently regulate enhancer chromatin accessibility, affecting zygotic gene expression in zebrafish embryos.

31 citations

zebrafishATAC-seq

𝕏 PostBluesky