Differential efficacy of α5IA in the Dp(16)1Yey mouse model of Down syndrome: implications for translational research
Jérémy Jehl, Valérie Nalesso, Claire Chevalier…·Yann Hérault
This study evaluates the efficacy of 5IA in the Dp(16)1Yey mouse model of Down syndrome, finding improved motor coordination but no cognitive rescue, suggesting divergent pathophysiology compared to Ts65Dn models.