GenomicsCell ReportsPeer-reviewed
Epigenome dysregulation resulting from NSD1 mutation in head and neck squamous cell carcinoma
Nargess Farhangdoost, Cynthia Horth, Bo Hu…·Jacek Majewski
This study investigates the epigenetic and transcriptomic effects of NSD1 mutations in head and neck squamous cell carcinoma, showing loss of H3K36me2 and DNA methylation, and gain of H3K27me3, leading to gene expression changes.