Author

Mariel Coradin

University of PennsylvaniaORCID 0000-0003-3560-4384Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 1 Genomics· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Assay:ChIP-seq· 2 Research Focus:differential expression· 2 Assay:DNA methylation· 2 Research Focus:gene regulatory network inference· 2 Organism:mouse· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Approach:experimental assay· 1

Frequent Co-Authors

Benjamin Aaron GarciaiD· 2 shared Francisca N. de Luna VitorinoiD· 2 shared Peder J. LundiD· 2 shared Simone SidoliiD· 2 shared Benjamin A. GarciaiD· 1 shared Bo HuiD· 1 shared Chao LüiD· 1 shared Charles W.M. RobertsiD· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersDevelopmental Biology

Benjamin Aaron GarciaORCID

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3 papers

Recent·Most cited

Developmental BiologyJournal of Biological ChemistryPeer-reviewedApr 10, 2026

Cleavage of histone H2A during embryonic stem cell differentiation destabilizes nucleosomes to counteract gene activation

Mariel Coradin, Elizabeth G. Poulsen Porter, Francisca N. de Luna Vitorino…·Benjamin Aaron Garcia

The paper shows that cleavage of histone H2A by Cathepsin L during ESC differentiation reduces nucleosome stability and counteracts gene activation.

2 citations

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GenomicsCell ReportsPeer-reviewedFeb 1, 2021

Epigenome dysregulation resulting from NSD1 mutation in head and neck squamous cell carcinoma

Nargess Farhangdoost, Cynthia Horth, Bo Hu…·Jacek Majewski

This study investigates the epigenetic and transcriptomic effects of NSD1 mutations in head and neck squamous cell carcinoma, showing loss of H3K36me2 and DNA methylation, and gain of H3K27me3, leading to gene expression changes.

67 citationstop 4%

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Systems BiologybioRxivPreprintAug 17, 2020

PROFILING OF Y1 CELLS TREATED WITH FGF-2 REVEALS PARALLELS WITH ONCOGENE-INDUCED SENESCENCE

Peder J. Lund, Mariana de Camargo Lopes, Simone Sidoli…·Benjamin Aaron Garcia

The paper profiles Y1 cells treated with FGF-2, revealing epigenetic and transcriptomic changes consistent with oncogene-induced senescence.

DOI 10.1101/2020.08.17.247023

mouseproteomics

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