Author

Zihao Chen

University of EdinburghORCID 0000-0002-8221-0751Unclaimed ORCID profile · follow to get notified of new preprints

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Zihao Chen7 papers · Hong Kong Polytechnic University

Biology Disciplines

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Molecular Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Assay:electronic health records· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1

Frequent Co-Authors

Achim C. SchnauferiD· 1 shared Addison FreseiD· 1 shared Aisling KennyiD· 1 shared Alasdair C. IvensiD· 1 shared Andrew C. StanfieldiD· 1 shared Cody GoodeiD· 1 shared Damien WrightiD· 1 shared Danai KatsanevakiiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

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10 top collaborators · 21 mutual co-author links

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1 shared paperMolecular Biology

Achim C. SchnauferORCID

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2 papers

Recent·Most cited

Noradrenergic-dependent restoration of visual discrimination in a mouse model of SYNGAP1-related disorder

Danai Katsanevaki, Nathalie Dupuy, Sam A. Booker, Damien Wright, Aisling Kenny, Zihao Chen, Nina Kudryashova, Pippa Howitt, Andrew C. Stanfield, Peter C. Kind, Nathalie L. Rochefort

This study shows that noradrenergic modulation can restore visual discrimination in a SYNGAP1 mouse model by improving coding precision in the primary visual cortex.

bioRxiv · Apr 9, 2025 · PreprintNeuroscience

KREH2 helicase represses ND7 mRNA editing in procyclic-stage Trypanosoma brucei by opposite modulation of canonical and moonlighting gRNA utilization creating a proposed mRNA structure

Joshua Meehan, Alasdair C. Ivens, Scott L. Grote, Tyler Rodshagen, Zihao Chen, Cody Goode, Sunil K Sharma, Vikas Kumar, Addison Frese, Zachary Goodall, Laura McCleskey, Rebecca Sechrist, Lanying Zeng, Nicholas Jon Savill, Silvi Rouskin, , Jorge Cruz‐Reyes

The paper identifies KREH2 helicase as a repressor of ND7 mRNA editing in T. brucei by modulating canonical and moonlighting gRNA utilization, revealing its dual role in developmental editing control.

Nucleic Acids Research · Aug 16, 2024Peer-reviewedMolecular Biology