Cancer BiologyScience AdvancesPeer-reviewed
Modulation of blood-tumor barrier transcriptional programs improves intra-tumoral drug delivery and potentiates chemotherapy in GBM
Jorge L. Jimenez-Macias, Philippa C. Vaughn-Beaucaire, Ayush Bharati…·Sean Edward Lawler
This study identifies a 12-gene BTB signature, shows CDH5 as a core component, and demonstrates that BIA disrupts the BTB to enhance chemotherapy delivery and efficacy in GBM.
24 citationstop 1%