Venugopal Nair

Simplifying principles underlying the highly complex peptide motif of the promiscuous chicken class I molecule, BF2*21:01

The paper identifies simplifying principles governing peptide binding by the promiscuous chicken class I molecule BF2*21:01, revealing patterns that enable broad peptide repertoire while maintaining stable binding.

High-Fidelity Long-Read Sequencing of an Avian Herpesvirus Reveals Extensive Intrapopulation Diversity in Tandem Repeat Regions

The paper uses long-read sequencing to analyze intrapopulation diversity in tandem repeat regions of Mareks disease virus strains, revealing phenotypic links to virulence and attenuation.

Pervasive differential splicing in Marek’s Disease Virus can discriminate CVI-988 vaccine strain from RB-1B virulent strain in chicken embryonic fibroblasts

ALV-J and REV synergistically activate a new oncogene of KIAA1199 via NF-κB and EGFR signaling regulated by miR-147

This study identifies KIAA1199 as a new oncogene activated by ALV-J and REV synergism through NF-κB and EGFR pathways, with miR-147 suppression maintaining pathway crosstalk.