Simplifying principles underlying the highly complex peptide motif of the promiscuous chicken class I molecule, BF2*21:01
Michael Harrison, Paul E. Chappell, Samer Halabi, Maria Danysz, Enock Mararo, Łukasz Magiera, Clemens Hermann, Michael J. Deery, Kathryn Susan Lilley, Hans‐Joachim Wallny, David W Avila, William N. Mwangi, Venugopal Nair, Susan M. Lea, Nicola Ternette, Jim Kaufman
The paper identifies simplifying principles governing peptide binding by the promiscuous chicken class I molecule BF2*21:01, revealing patterns that enable broad peptide repertoire while maintaining stable binding.
bioRxiv · Jun 30, 2026 · PreprintImmunology