Author

M. Amin Arnaout

Harvard UniversityORCID 0000-0002-8270-0371Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

M. Amin Arnaout1 paper

Biology Disciplines

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Molecular Biology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 1 Assay:imaging· 1 Organism:mouse· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Brian D. Adair· 2 shared Jian-Ping XiongiD· 2 shared Johannes F. Van AgthoveniD· 2 shared José L. Alonso· 2 shared Clary B. ClishiD· 1 shared Conroy O. FieldiD· 1 shared David A. TessiD· 1 shared Donald W. LandryiD· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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2 shared papersPathology

Brian D. Adair

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2 papers

Recent·Most cited

PathologyNature CommunicationsPeer-reviewedOct 4, 2024

Platelet integrin αIIbβ3 plays a key role in venous thrombogenesis in a mouse model

Brian D. Adair, Conroy O. Field, José L. Alonso…·M. Amin Arnaout

This paper shows that m-tirofiban, a non-partial agonist of IIbβ3, effectively inhibits venous thrombosis without increasing bleeding in a mouse model.

19 citationstop 3%

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Molecular BiologyStructurePeer-reviewedJul 25, 2019

Structural basis of the differential binding of engineered knottins to integrins αVβ3 and α5β1

Johannes F. Van Agthoven, Hengameh Shams, Frank V. Cochran…·M. Amin Arnaout

The paper determines the structures of engineered knottins 2.5F and 2.5D in complex with integrin αVβ3 and reveals structural mechanisms underlying their differential binding to αVβ3 and α5β1.

16 citations

protein structureexperimental assay

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