Author

Monsef Benkirane

Centre National de la Recherche ScientifiqueORCID 0000-0002-8286-4405Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Cell Biology· 1 Genomics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1

Frequent Co-Authors

Olivier CuvieriD· 2 shared Ahmad YatimiD· 1 shared Alexandre HeurteauiD· 1 shared Andrew Z. FireiD· 1 shared Bijan SobhianiD· 1 shared Cécile M. Doyen· 1 shared Cyprien Jahan· 1 shared David DepierreiD· 1 shared

Activity by Year

2019-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCell Biology

Olivier CuvierORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

MacroH2A1 and H3K27me3 target cGAS to facultative heterochromatin to restrain innate immune activation

Suzie Thenin-Houssier, Cyprien Jahan, Wenjie Xu, Giorgio Lucio Papadopoulos, Lucie Bonnet‐Madin, Syota Matsumoto, Tomoya Kujirai, Olivier Cuvier, Hitoshi Kurumizaka, Bijan Sobhian, Monsef Benkirane

This study shows that macroH2A1 and H3K27me3 bind cGAS to sequester it in heterochromatin, preventing innate immune activation.

bioRxiv · Oct 9, 2026 · PreprintCell Biology

Combined direct/indirect detection allows identification of DNA termini in diverse sequencing datasets and supports a multiple-initiation-site model for HIV plus-strand synthesis

William Yang Wang, Karen L. Artiles, Shinichi Machida, Monsef Benkirane, Nimit Jain, Andrew Z. Fire

The paper introduces a computational method to detect DNA termini using direct and indirect readouts, revealing multiple initiation sites for HIV plus-strand synthesis.

bioRxiv · Jun 12, 2023 · PreprintGenomics

NOTCH assembles a transcriptional repressive complex containing NuRD and PRC1 to repress genes involved in cell proliferation and differentiation.

Cécile M. Doyen, David Depierre, Ahmad Yatim, Alexandre Heurteau, Jean‐Daniel Lelièvre, Yves Lévy, Olivier Cuvier, Monsef Benkirane

bioRxiv · Jan 15, 2019 · PreprintMolecular Biology