Author

Shinichi Machida

Centre National de la Recherche ScientifiqueORCID 0009-0002-8891-4888Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Genomics· 1 Microbiology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:human· 2 Assay:bulk RNA-seq· 1 Assay:cryo-EM· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Approach:microscopy & imaging analysis· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Andrew Z. FireiD· 1 shared Hiroki Tanaka· 1 shared Karen L. ArtilesiD· 1 shared Katsumi MaenakaiD· 1 shared Mina SasakiiD· 1 shared Minoru Fukushima· 1 shared Monsef BenkiraneiD· 1 shared Nimit JainiD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperGenomics

Andrew Z. FireORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

MicrobiologyNature CommunicationsPeer-reviewedSep 22, 2026

Structural basis of lenacapavir-induced HIV-1 capsid disruption during virion maturation

Hiroki Tanaka, Reina Morita, Tomomasa Oka…·Shinichi Machida

This study determines the cryo-EM structure of HIV-1 capsid lattice with lenacapavir, showing how it disrupts capsid formation and function during virion maturation.

1 citation

humancryo-EM

𝕏 PostBluesky

GenomicsbioRxivPreprintJun 12, 2023

Combined direct/indirect detection allows identification of DNA termini in diverse sequencing datasets and supports a multiple-initiation-site model for HIV plus-strand synthesis

William Yang Wang, Karen L. Artiles, Shinichi Machida…·Andrew Z. Fire

The paper introduces a computational method to detect DNA termini using direct and indirect readouts, revealing multiple initiation sites for HIV plus-strand synthesis.

1 citation

humanbulk RNA-seq

𝕏 PostBluesky