Robert W. Grange

Voluntary Running Sustains the Correction of Inflammation-Related Gene Expression Conferred by AAV Gene Therapy in Mdx Mice

The paper shows that voluntary running maintains gene expression corrections from AAV gene therapy in mdx mice, indicating physical exercise does not negatively affect therapy outcomes.

Age-dependent remodeling of the sciatic proteome in 5xFAD mice can be attenuated by exercise or donepezil treatment to maintain neuromuscular function

This study shows that exercise or donepezil treatment can reduce proteomic changes in sciatic nerves of 5xFAD mice, preserving neuromuscular function before cognitive decline.