Author

Michiko Shirane

Nagoya City UniversityORCID 0000-0002-8297-9245Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1 Research Focus:metabolism & bioenergetics· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Honoka Maki· 2 shared Hizuki Takahashi· 1 shared Kazuhiro NakamuraiD· 1 shared Mei Kamino· 1 shared Miki Iwata· 1 shared Nagi MukaeiD· 1 shared Tomoya OzakiiD· 1 shared Yumi Morisugi· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 22 mutual co-author links

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2 shared papersCell Biology

Honoka Maki

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2 papers

Recent·Most cited

Cell BiologyTrafficPeer-reviewedOct 25, 2026

TMEM55B regulates lysosomal acidification and ER-lysosome calcium signaling to promote lipolysis

Nagi Mukae, Honoka Maki, Michiko Shirane

This study identifies TMEM55B as a regulator of lysosomal acidification and ER-lysosome calcium signaling, which promotes lipolysis and cholesterol metabolism.

DOI 10.1111/tra.70057

humanproteomics

𝕏 PostBluesky

NeurosciencebioRxivPreprintOct 21, 2025

Impaired cholesterol homeostasis in SNr parvalbumin neurons disrupts basal ganglia circuitry for action selection

Tomoya Ozaki, Yumi Morisugi, Mei Kamino…·Michiko Shirane

This study shows that impaired cholesterol homeostasis in SNr parvalbumin neurons disrupts basal ganglia circuitry, leading to ADHD-like behaviors.

DOI 10.1101/2025.10.21.683627

mouseexperimental assay

𝕏 PostBluesky