R2TP-like Quaternary Chaperones: a comprehensive overview to understand the dynamic R2SP complex
Paulo E. Santo, Marie-Eve Chagot, Hugo Gizardin-Fredon, Marie Ley, Thomas Chenuel, Evolène Deslignière, Laura Plassart, Ana C. F. Paiva, Pedro M. F. Sousa, Édouard Bertrand, Bruno Charpentier, Céline Verheggen, Marc Quinternet, Philippe Meyer, Tiago M. Bandeiras, , Xavier Manival
This study investigates the 3D structure and function of the human R2SP complex using biochemical and structural methods, revealing similarities to the canonical R2TP complex and differences in ATPase activity and adaptor binding.
bioRxiv · Jan 27, 2025 · PreprintBiophysics