Célia Plisson‐Chastang

CDC25B couples ribosome biogenesis to cell cycle kinetics to promote spinal cord neurogenesis

The paper shows CDC25B promotes spinal cord neurogenesis by coordinating cell cycle progression with ribosome biogenesis, leading to increased translation in differentiating neurons.

The R2T(P) complex orchestrates the SHQ1 driven early steps of box H/ACA snoRNP maturation

This paper identifies a novel role for the R2T complex in early box H/ACA snoRNP maturation by characterizing interactions between SHQ1, RuvBL1:RuvBL2, and other factors.

Translatome and translation dynamics analysis of a RiboCancer cell line panel reveals that leukemia-associated Rps15 mutations rewire translation through codon-specific tRNA accommodation defects.

The paper analyzes translatome and translation dynamics in RiboCancer cell lines to show that Rps15 mutations disrupt tRNA accommodation, affecting translation efficiency and transcriptional regulation in CLL.

Organelle distribution and protein translation defects in radial glia cells with mutations in Eml1

The paper investigates Eml1 mutations in mice, finding altered organelle distribution and translation defects in radial glia cells, contributing to subcortical heterotopia.

R2TP-like Quaternary Chaperones: a comprehensive overview to understand the dynamic R2SP complex

This study investigates the 3D structure and function of the human R2SP complex using biochemical and structural methods, revealing similarities to the canonical R2TP complex and differences in ATPase activity and adaptor binding.

Probing small ribosomal subunit RNA helix 45 acetylation across eukaryotic evolution

The paper investigates the role of SNORD13 in rRNA acetylation across eukaryotes, showing its requirement in human and zebrafish but not in yeast or C. elegans.

The final step of 40S ribosomal subunit maturation is controlled by a dual key lock

The paper identifies a dual key lock mechanism involving RIO1 and RPS26 that controls the final maturation step of 40S ribosomal subunits by displacing DIM2 and enabling NOB1-mediated cleavage of 18S rRNA.