Laura Plassart

Translatome and translation dynamics analysis of a RiboCancer cell line panel reveals that leukemia-associated Rps15 mutations rewire translation through codon-specific tRNA accommodation defects.

The paper analyzes translatome and translation dynamics in RiboCancer cell lines to show that Rps15 mutations disrupt tRNA accommodation, affecting translation efficiency and transcriptional regulation in CLL.

R2TP-like Quaternary Chaperones: a comprehensive overview to understand the dynamic R2SP complex

This study investigates the 3D structure and function of the human R2SP complex using biochemical and structural methods, revealing similarities to the canonical R2TP complex and differences in ATPase activity and adaptor binding.

The final step of 40S ribosomal subunit maturation is controlled by a dual key lock

The paper identifies a dual key lock mechanism involving RIO1 and RPS26 that controls the final maturation step of 40S ribosomal subunits by displacing DIM2 and enabling NOB1-mediated cleavage of 18S rRNA.