Neutralizing human monoclonal antibodies that target the PcrV component of the Type III Secretion System of Pseudomonas aeruginosa act through distinct mechanisms
Jean-Mathieu Desveaux, Éric Faudry, Carlos Contreras‐Martel, François C. Cretin, Leonardo Sebastián Dergan‐Dylon, Axelle Amen, Isabelle Bally, Victor TardivyCasemajor, Fabien Chenavier, Delphine Fouquenet, Yvan Caspar, Ina Attrée, Andréa Dessen, Pascal Poignard
The paper isolates and characterizes human monoclonal antibodies against PcrV of Pseudomonas aeruginosa T3SS, revealing distinct mechanisms of T3SS inhibition.
eLife · Feb 17, 2026Peer-reviewedMicrobiology