Delphine Fouquenet

This study identifies a complement-inflammasome signaling axis that drives excessive inflammation during Pseudomonas aeruginosa and Aspergillus fumigatus co-infection in cystic fibrosis patients.

The paper isolates and characterizes human monoclonal antibodies against PcrV of Pseudomonas aeruginosa T3SS, revealing distinct mechanisms of T3SS inhibition.

This study identifies cis-aconitate as a dual-action antiviral and anti-inflammatory agent that reduces influenza mortality in mice by targeting viral polymerase and ERK/AKT/NF-κB signaling.

This study shows that CFTR modulators do not affect the growth of Aspergillus fumigatus in vitro, despite reducing its colonization in patients.