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Elongasome Dysfunction Triggers Dependence on MepM-Mediated Peptidoglycan Recycling

This study identifies MepM-mediated peptidoglycan recycling as essential for bacterial survival when elongasome function is impaired, highlighting its potential as a target for antibacterial therapies.

Neutralizing human monoclonal antibodies that target the PcrV component of the Type III Secretion System of Pseudomonas aeruginosa act through distinct mechanisms

The paper isolates and characterizes human monoclonal antibodies against PcrV of Pseudomonas aeruginosa T3SS, revealing distinct mechanisms of T3SS inhibition.

Strain-Specific Variation in the Complement Resistome of Pseudomonas aeruginosa

This study identifies strain-specific and common mechanisms of complement resistance in Pseudomonas aeruginosa using Tn-seq, highlighting key factors like Ssg and Crc.

Functional and pangenomic exploration of Roc two-component regulatory systems identifies novel players across Pseudomonas species

This paper identifies a new regulator, RocA3, and expands the Roc two-component regulatory system in Pseudomonas species, revealing its evolutionary plasticity and role in virulence.

Avirulent Pseudomonas aeruginosa T3SS-negative strains belonging to Clade 5 produce variable quantities of secondary metabolites

The paper characterizes avirulent P. aeruginosa strains lacking T3SS genes, showing they produce variable secondary metabolites despite low cytotoxicity.