Author

Haig K. Aghajanian

University of PennsylvaniaORCID 0000-0002-8317-0157Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

Adi LightstoneiD· 1 shared Bruno CogliatiiD· 1 shared Chittampalli N. YashaswiniiD· 1 shared Hamideh ParhiziD· 1 shared Joel G. RurikiD· 1 shared Jonathan A. EpsteiniD· 1 shared Kenneth LiiD· 1 shared Li CheniD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperCell Biology

Adi LightstoneORCID

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1 paper

Recent·Most cited

In vivo anti-FAP CAR T therapy reduces fibrosis and restores liver homeostasis in metabolic dysfunction-associated steatohepatitis

Chittampalli N. Yashaswini, Bruno Cogliati, Tianyue Qin, Tran To, Thomas Williamson, Tyler Ellis Papp, Kenneth Li, Raisa B. Rasul, Li Chen, Adi Lightstone, Haig K. Aghajanian, Hamideh Parhiz, Shuang Wang, Joel G. Rurik, Jonathan A. Epstein, Scott L. Friedman

This study evaluates in vivo anti-FAP CAR T therapy for MASH, showing reduced fibrosis and restored liver homeostasis through HSC depletion and immune modulation.

bioRxiv · Feb 25, 2025 · PreprintCell Biology